Finally, take control of study milestones
The agentic AI platform built to accelerate your study
AI-Powered Clinical Trial Site Intelligence
Across the industry, 37% of sites enroll poorly, and 11% never enroll a single patient.* SYNETIC™ by PSI was built to change that. By harnessing AI and semantic intelligence, the platform eliminates underperforming sites, improves site-selection accuracy, and shortens startup timelines from months to days.
The result: Faster enrollment, lower operational risk, and trials that stay on time.
How SYNETIC™ Works
SYNETIC™ is the intelligence behind PSI. It connects data from more than 500,000 institutions, 3 million study sites, and 300,000 clinical projects into a continuously learning system.
Every day, clinical teams lose valuable time navigating outdated site lists and fragmented data. SYNETIC™ changes that. With advanced semantic modeling, AI-driven reasoning, and intuitive knowledge graphs, SYNETIC™ brings together years of global site performance data to pinpoint the best-fit sites for every protocol – before a single feasibility email is sent.
For sponsors, this means faster access to evidence-based insights, so decisions are made with greater speed, clarity, and confidence, from planning through execution.
* Tufts CSDD, 2024: “Clinical Site Enrollment Performance Trends.”
500,000
institutions
3,000,000
study sites
300,000
clinical projects
What are the benefits for our sponsors?
- Find the right sites faster: Our sponsors can generate ranked site lists in seconds, using verified global data you can trust.
- Select sites with confidence: Automated scoring evaluates site performance, therapeutic expertise, and current workload – so you choose sites that fit your protocol, not just your timeline.
- Plan for realistic recruitment: For each site, predictive feasibility models, trained on historical enrollment data, help you forecast recruitment potential and focus outreach where it will work.
- De-risk pivotal studies: SYNETIC™ visualizes relationships between institutions, investigators, and study designs to help you make more informed planning decisions for complex programs.
- Make decisions as your study evolves: SYNETIC™ delivers real-time, evidence-based insights through a next-gen semantic data architecture designed to support consistent, connected decision-making across the study lifecycle.
Key SYNETIC™ features
Next-gen, multi-modal hybrid semantic data platform for predictive insights based on complex relationships of all data types
AI-enabled: OmniRAG approach with advanced reasoning LLMs for in-depth analysis of real-time data, precise protocol matching, and instant site ranking
PSI enterprise ontology for accuracy in semantic search and discovery of hidden insights
MCP server technology for the orchestration of powerful multi-skilled agents
Learn more about our relentless innovation to deliver clinical trials on time and on budget
VISIONAL™
Financial and clinical feasibility modeling
PSI proprietary cloud-based platform
SYNETIC™ is part of PSI’s award-winning INTELIA™ platform, a suite of advanced tools for clinical trial planning and conduct.
INTELIA™ brings together a suite of clinical trial planning tools:
- SYNETIC™ site and study knowledge engine
- VISIONAL™ financial and clinical feasibility modeling
- CLARITY™ study budgeting and forecasting
- CADENCE™ study budget tracking and reporting
- INSITE™ investigator grant calculator
- PACE™ smart monitoring planning
Deliver Your Pivotal Trial on Time, Every Time
For 30 years, PSI has set the benchmark in operational reliability. Now, with SYNETIC™, that precision meets agentic AI. We’re not just speeding up study startup. We’re redefining what on time means for clinical research.
PSI and Sanofi at SCOPE 2026
Discover how quickly identify high-performing sites, streamline operational processes, and accelerate patient enrolment in New Approach to Site ID: Adding a Semantic Knowledge Platform to Solid Process Foundation, presented by Sanofi and PSI at SCOPE Summit 2026.
- February 3rd, 11:55 am, Site Engagement track
