Neuroscience CRO Services
Enroll pivotal CNS trials on schedule with deep expertise and site relationships
Running CNS trials on time and on budget can be as complex as the brain itself. Stay the course with our long-standing partnerships with hundreds of experienced institutions and deep expertise in managing the complexities of pivotal neurology trials.
10
CNS drug approvals
20+
years of CNS Experience on leadership team
93%
on-time enrollment
Neurology Pivotal Trial Solutions
Due to their complexity and high levels of competition, trials in central nervous system disorders require specialized expertise and excellent relationships with productive sites. With development expanding into gene therapy and radiopharmaceuticals, each modality presents its own unique set of challenges.
To deliver your novel CNS drug to market faster, you need your study to stand out. With over 25 years of CNS trial experience in multiple sclerosis, Parkinson’s disease, Alzheimer’s, and more, PSI’s services help you succeed by using our extensive global site network and strategies to ensure sites prioritize your study.
PSI Neurology Highlights
- 10 neurology drug approvals
- 75% of multiple sclerosis drug approvals in past 5 years
- Expertise in adult and pediatric populations
- Expertise in managing multi-disciplinary teams at the site level
- Dedicated support for emerging technologies and methodologies, including advances in neuroimaging and data analytics
PSI MS & Other CNS Therapeutic Expertise
| Disease Type | Neuroinflammatory / Demyelinating Disorders | Multiple Sclerosis
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| Neurodegenerative Disorders |
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| Acute Neurological Events | Stroke | |
| Movement Disorders | Cervical Dystonia | |
| Pain and Sensory Disorders | Pain Studies | |
| CNS Agents | DMDs |
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| Symptomatic Treatment | Spasticity |
Specialized Neurology Trial Support Services
Regional and Global CNS Feasibility Expertise
Timely CNS study delivery depends on precise site selection. PSI enhances decision-making with access to site historical performance, operational capacity, and recruitment potential by indication through SYNETIC™, part of PSI’s INTELIA™ clinical trial planning platform. SYNETIC™ helps find the best mix of high-performing sites for your protocol.
Our feasibility assessments go beyond the basics to provide a full picture of site performance and landscape, including:
- Target population availability and limiting factors
- Standards of care
- Competitive studies
- Regulatory climate
- Access to Key Opinion Leaders
With a database of proven neurology sites offering significantly higher enrollment rates and the advanced VISIONAL™ study modeling solution, PSI makes it easier than ever to select the optimal sites and geographies for your program. Our unique combination of data-driven site selection and predictive modeling maximizes your study’s visibility and potential for success.
Strong Site Relationships and Support
It’s not enough simply to identify the right sites — you need to know how to work with them as well. This includes investing in training and dedicated support for successful patient enrollment and retention. PSI’s approach centers on long-term partnership, consistent support, and shared goals, ensuring that sites view your study as a priority and are committed to its success. Our full-service site support includes:
- Providing integrated rater training
- Regular onsite and remote training on study protocols and patient interaction to efficiently meet study requirements
- Comprehensive study manuals and quick-reference guides for consistent execution
- Digital communication tools for real-time updates and speedy problem-solving
- 24/7 dedicated support teams to quickly address urgent issues and avoid delays
- Advanced data systems for seamless data management, reducing errors and ensuring real-time accuracy
- Recruitment strategies refined through demographic and site-specific analysis to boost enrollment and retention
- Tailored imaging assistance for high-quality operations
- Optimizing patient pathways for each site and patient group
- Assisting with site-specific startup activities, including reviews, approvals, and contract negotiations
- Coordination with central and local labs for clear guidance and investigator training on storage and logistics
A Forward-Thinking Approach to Neurology Research
Technological advances, evolving patient needs, and increasing competition are driving significant changes in the neurology research landscape. Each requires careful attention to trial design, geography, and patient enrollment; a trial for a biosimilar is very different from that for a novel gene therapy drug, but delivering it can be just as challenging.
Your study deserves a CRO committed to understanding and navigating these complexities. PSI stands out with expertise spanning global 10-year CNS programs, biosimilar studies, and specialized teams dedicated to cell and gene therapy and radiopharmaceutical studies. Our neurology experts have the answers to help you enroll your study as quickly and efficiently as possible while ensuring quality and consistency.
Get in touch with PSI’s Neurology team
Your pivotal neurology trial requires seamless delivery. Trust the CRO built for speed, accuracy, and stability — find your team of neurology experts with PSI today.
Trusted to Deliver
When you partner with PSI, you work with a team recognized by independent industry organizations and sponsor surveys for what matters most in clinical research: expertise, consistent operational excellence, and reliable delivery.
